The overdose epidemic in the U.S. is a major public health crisis that hasn't leveled off. Fentanyl now turns up in drug supplies where users never expect it, and xylazine — an animal sedative often called “tranq”, not reversed by naloxone alone — has become a common adulterant in much of the country. Harm reduction supply has had to expand to match that reality, and this category reflects that.

Naloxone nasal spray is still the core of it — a fast-acting reversal for opioid overdose, available over-the-counter and stocked for moments when minutes matter. Alongside it, we carry fentanyl and xylazine combo test strips, which let someone check a substance before using it instead of finding out the hard way. Different tool, same goal: fewer preventable deaths.

Health departments and public health programs are our largest buyers here, often ordering naloxone and test strips together in bulk for community distribution. Schools, universities, and shelters round out demand. It's why HofCare treats this category with more urgency than a routine reorder — the people relying on it don't have room for a delay.